Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

Voltage-gated KCNQ1 (Kv7.1) potassium channels are expressed abundantly in heart but they are also found in multiple other tissues. Differential coassembly with single transmembrane KCNE beta subunits in different cell types gives rise to a variety of biophysical properties, hence endowing distinct...

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Autors principals: Yu, Haibo, Lin, Zhihong, Mattmann, Margrith E., Zou, Beiyan, Terrenoire, Cecile, Zhang, Hongkang, Wu, Meng, McManus, Owen B., Kass, Robert S., Lindsley, Craig W., Hopkins, Corey R., Li, Min
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666726/
https://ncbi.nlm.nih.gov/pubmed/23650380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300684110
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