Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

Voltage-gated KCNQ1 (Kv7.1) potassium channels are expressed abundantly in heart but they are also found in multiple other tissues. Differential coassembly with single transmembrane KCNE beta subunits in different cell types gives rise to a variety of biophysical properties, hence endowing distinct...

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Detalles Bibliográficos
Main Authors: Yu, Haibo, Lin, Zhihong, Mattmann, Margrith E., Zou, Beiyan, Terrenoire, Cecile, Zhang, Hongkang, Wu, Meng, McManus, Owen B., Kass, Robert S., Lindsley, Craig W., Hopkins, Corey R., Li, Min
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666726/
https://ncbi.nlm.nih.gov/pubmed/23650380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300684110
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