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Identification of novel small molecule modulators of K(2P)18.1 two-pore potassium channel

Two-pore domain potassium (K(2P)) channels are responsible for background potassium (K(+)) current, which is crucial for the maintenance of resting membrane potential. K(2P)18.1, also called TWIK-related spinal cord K(+) channel (TRESK) or KCNK18, is thought to be a major contributor to background K...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Bruner, J. Kyle, Zou, Beiyan, Zhang, Hongkang, Zhang, Yixin, Schmidt, Katharina, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222048/
https://ncbi.nlm.nih.gov/pubmed/24972239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.06.021
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