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PKC-dependent activation of human K(2P)18.1 K(+) channels

BACKGROUND AND PURPOSE: Two-pore-domain K(+) channels (K(2P)) mediate K(+) background currents that modulate the membrane potential of excitable cells. K(2P)18.1 (TWIK-related spinal cord K(+) channel) provides hyperpolarizing background currents in neurons. Recently, a dominant-negative loss-of-fun...

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Autori principali: Rahm, Ann-Kathrin, Gierten, Jakob, Kisselbach, Jana, Staudacher, Ingo, Staudacher, Kathrin, Schweizer, Patrick A, Becker, Rüdiger, Katus, Hugo A, Thomas, Dierk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417503/
https://ncbi.nlm.nih.gov/pubmed/22168364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01813.x
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