Carvedilol targets human K(2P)3.1 (TASK1) K(+) leak channels

BACKGROUND AND PURPOSE: Human K(2P)3.1 (TASK1) channels represent potential targets for pharmacological management of atrial fibrillation. K(2P) channels control excitability by stabilizing membrane potential and by expediting repolarization. In the heart, inhibition of K(2P) currents by class III a...

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Detalhes bibliográficos
Main Authors: Staudacher, K, Staudacher, I, Ficker, E, Seyler, C, Gierten, J, Kisselbach, J, Rahm, A-K, Trappe, K, Schweizer, PA, Becker, R, Katus, HA, Thomas, D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130955/
https://ncbi.nlm.nih.gov/pubmed/21410455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01319.x
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