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Comparative Analyses of N-Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing

Bacterial quorum sensing is mediated by low molecular-weight signals and plays a critical role in both the pathogenesis of infectious disease and beneficial symbioses. There is significant interest in the development of synthetic ligands that can intercept bacterial quorum sensing signals and modula...

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Hlavní autoři: Geske, Grant D., O’Neill, Jennifer C., Miller, David M., Wezeman, Rachel J., Mattmann, Margrith E., Lin, Qi, Blackwell, Helen E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593081/
https://ncbi.nlm.nih.gov/pubmed/18224645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200700551
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