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Modulation of Bacterial Quorum Sensing with Synthetic Ligands: Systematic Evaluation of N-Acylated Homoserine Lactones in Multiple Species and New Insights into Their Mechanisms of Action

Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathogenesis of infectious disease and in beneficial symbioses. There is intense interest in the developme...

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Detalhes bibliográficos
Main Authors: Geske, Grant D., O’Neill, Jennifer C., Miller, David M., Mattmann, Margrith E., Blackwell, Helen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592086/
https://ncbi.nlm.nih.gov/pubmed/17927181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja074135h
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