載入...
Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M(1) Positive Allosteric Modulators
This Letter describes the chemical optimization of a new series of muscarinic acetylcholine receptor subtype 1 (M(1)) positive allosteric modulators (PAMs) based on novel tricyclic triazolo- and imidazopyridine lactam cores, devoid of M(1) agonism, e.g., no M(1) ago-PAM activity, in high expressing...
Na minha lista:
| 發表在: | ACS Chem Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6456254/ https://ncbi.nlm.nih.gov/pubmed/30086237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00311 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|