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Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction

Clinical studies have revealed that genetic variations in metabotropic glutamate receptor 3 (mGlu(3)) affect performance on cognitive tasks dependent upon the prefrontal cortex (PFC) and may be linked to psychiatric conditions such as schizophrenia, bipolar disorder, and addiction. We have performed...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Walker, Adam G., Wenthur, Cody J., Xiang, Zixiu, Rook, Jerri M., Emmitte, Kyle A., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313856/
https://ncbi.nlm.nih.gov/pubmed/25583490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416196112
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