A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors

GspB is a serine-rich repeat (SRR) adhesin of Streptococcus gordonii that mediates binding of this organism to human platelets via its interaction with sialyl-T antigen on the receptor GPIbα. This interaction appears to be a major virulence determinant in the pathogenesis of infective endocarditis....

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Detalhes bibliográficos
Main Authors: Pyburn, Tasia M., Bensing, Barbara A., Xiong, Yan Q., Melancon, Bruce J., Tomasiak, Thomas M., Ward, Nicholas J., Yankovskaya, Victoria, Oliver, Kevin M., Cecchini, Gary, Sulikowski, Gary A., Tyska, Matthew J., Sullam, Paul M., Iverson, T. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131266/
https://ncbi.nlm.nih.gov/pubmed/21765814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002112
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