A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors

GspB is a serine-rich repeat (SRR) adhesin of Streptococcus gordonii that mediates binding of this organism to human platelets via its interaction with sialyl-T antigen on the receptor GPIbα. This interaction appears to be a major virulence determinant in the pathogenesis of infective endocarditis....

Full description

Saved in:
Bibliographic Details
Main Authors: Pyburn, Tasia M., Bensing, Barbara A., Xiong, Yan Q., Melancon, Bruce J., Tomasiak, Thomas M., Ward, Nicholas J., Yankovskaya, Victoria, Oliver, Kevin M., Cecchini, Gary, Sulikowski, Gary A., Tyska, Matthew J., Sullam, Paul M., Iverson, T. M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131266/
https://ncbi.nlm.nih.gov/pubmed/21765814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002112
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items