Identification of potential immunotherapeutic targets in antigen presentation and costimulation networks

Yazar: Spaapen, Robbert, Blomen, Vincent, van Veelen, Peter, Jongsma, Marlieke, Janssen, Lennert, Janssen, George, Raaben, Matthijs, Brummelkamp, Thijn, Neefjes, Jacques
Yayımlandı J Immunother Cancer (2014)

A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection

Yazar: Riblett, Amber M., Blomen, Vincent A., Jae, Lucas T., Altamura, Louis A., Doms, Robert W., Brummelkamp, Thijn R., Wojcechowskyj, Jason A.
Yayımlandı J Virol (2016)

Diverse viruses require the calcium transporter SPCA1 for maturation and spread

Yazar: Hoffmann, H.-Heinrich, Schneider, William M, Blomen, Vincent A, Scull, Margaret A, Hovnanian, Alain, Brummelkamp, Thijn R, Rice, Charles M
Yayımlandı Cell Host Microbe (2017)

Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents

Yazar: Gerhards, Nora M., Blomen, Vincent A., Mutlu, Merve, Nieuwenhuis, Joppe, Howald, Denise, Guyader, Charlotte, Jonkers, Jos, Brummelkamp, Thijn R., Rottenberg, Sven
Yayımlandı Mol Oncol (2018)

Generation of iPSCs from cultured human malignant cells

Yazar: Carette, Jan E., Pruszak, Jan, Varadarajan, Malini, Blomen, Vincent A., Gokhale, Sumita, Camargo, Fernando D., Wernig, Marius, Jaenisch, Rudolf, Brummelkamp, Thijn R.
Baskı/Yayın Bilgisi 2010

A haploid genetic screen identifies the G(1)/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity

Yazar: Heijink, Anne Margriet, Blomen, Vincent A., Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel A. T. M.
Yayımlandı Proc Natl Acad Sci U S A (2015)

E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes

Yazar: Sarbanes, Stephanie L., Blomen, Vincent A., Lam, Eric, Heissel, Søren, Luna, Joseph M., Brummelkamp, Thijn R., Falck-Pedersen, Erik, Hoffmann, H.-Heinrich, Rice, Charles M.
Yayımlandı Proc Natl Acad Sci U S A (2021)

NRP2 and CD63 are host factors for Lujo virus cell entry

Yazar: Raaben, Matthijs, Jae, Lucas T., Herbert, Andrew S., Kuehne, Ana I., Stubbs, Sarah H., Chou, Yi-ying, Blomen, Vincent A., Kirchhausen, Tomas, Dye, John M., Brummelkamp, Thijn R., Whelan, Sean P.
Yayımlandı Cell Host Microbe (2017)

Global gene disruption in human cells to assign genes to phenotypes

Yazar: Carette, Jan E., Guimaraes, Carla P., Wuethrich, Irene, Blomen, Vincent A., Varadarajan, Malini, Sun, Chong, Bell, George, Yuan, Bingbing, Muellner, Markus K., Nijman, Sebastian M., Ploegh, Hidde L., Brummelkamp, Thijn R.
Baskı/Yayın Bilgisi 2011

A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection

Yazar: Luteijn, Rutger D., van Diemen, Ferdy, Blomen, Vincent A., Boer, Ingrid G. J., Manikam Sadasivam, Saravanan, van Kuppevelt, Toin H., Drexler, Ingo, Brummelkamp, Thijn R., Lebbink, Robert Jan, Wiertz, Emmanuel J.
Yayımlandı J Virol (2019)

Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants

Yazar: Jacobson, Lee S., Lima, Heriberto, Goldberg, Michael F., Gocheva, Vasilena, Tsiperson, Vladislav, Sutterwala, Fayyaz S., Joyce, Johanna A., Gapp, Bianca V., Blomen, Vincent A., Chandran, Kartik, Brummelkamp, Thijn R., Diaz-Griffero, Felipe, Brojatsch, Jürgen
Baskı/Yayın Bilgisi 2013

Deciphering the Glycosylome of Dystroglycanopathies Using Haploid Screens for Lassa Virus Entry

Yazar: Jae, Lucas T., Raaben, Matthijs, Riemersma, Moniek, van Beusekom, Ellen, Blomen, Vincent A., Velds, Arno, Kerkhoven, Ron. M., Carette, Jan E., Topaloglu, Haluk, Meinecke, Peter, Wessels, Marja W., Lefeber, Dirk J., Whelan, Sean P., van Bokhoven, Hans, Brummelkamp, Thijn R.
Baskı/Yayın Bilgisi 2013

The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity

Yazar: Winter, Georg E., Radic, Branka, Mayor-Ruiz, Cristina, Blomen, Vincent A, Trefzer, Claudia, Kandasamy, Richard K., Huber, Kilian V.M., Gridling, Manuela, Chen, Doris, Klampfl, Thorsten, Kralovics, Robert, Kubicek, Stefan, Fernandez-Capetillo, Oscar, Brummelkamp, Thijn R., Superti-Furga, Giulio
Yayımlandı Nat Chem Biol (2014)

The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension

Yazar: Haarhuis, Judith H.I., van der Weide, Robin H., Blomen, Vincent A., Yáñez-Cuna, J. Omar, Amendola, Mario, van Ruiten, Marjon S., Krijger, Peter H.L., Teunissen, Hans, Medema, René H., van Steensel, Bas, Brummelkamp, Thijn R., de Wit, Elzo, Rowland, Benjamin D.
Yayımlandı Cell (2017)

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt‐based anti‐cancer drugs

Yazar: Planells‐Cases, Rosa, Lutter, Darius, Guyader, Charlotte, Gerhards, Nora M, Ullrich, Florian, Elger, Deborah A, Kucukosmanoglu, Asli, Xu, Guotai, Voss, Felizia K, Reincke, S Momsen, Stauber, Tobias, Blomen, Vincent A, Vis, Daniel J, Wessels, Lodewyk F, Brummelkamp, Thijn R, Borst, Piet, Rottenberg, Sven, Jentsch, Thomas J
Yayımlandı EMBO J (2015)

LZTR1 is a regulator of RAS ubiquitination and signaling

Yazar: Bigenzahn, Johannes W., Collu, Giovanna M., Kartnig, Felix, Pieraks, Melanie, Vladimer, Gregory I., Heinz, Leonhard X., Sedlyarov, Vitaly, Schischlik, Fiorella, Fauster, Astrid, Rebsamen, Manuele, Parapatics, Katja, Blomen, Vincent A., Müller, André C., Winter, Georg E., Kralovics, Robert, Brummelkamp, Thijn R., Mlodzik, Marek, Superti-Furga, Giulio
Yayımlandı Science (2018)

Enterovirus D68 receptor requirements unveiled by haploid genetics

Yazar: Baggen, Jim, Thibaut, Hendrik Jan, Staring, Jacqueline, Jae, Lucas T., Liu, Yue, Guo, Hongbo, Slager, Jasper J., de Bruin, Jost W., van Vliet, Arno L. W., Blomen, Vincent A., Overduin, Pieter, Sheng, Ju, de Haan, Cornelis A. M., de Vries, Erik, Meijer, Adam, Rossmann, Michael G., Brummelkamp, Thijn R., van Kuppeveld, Frank J. M.
Yayımlandı Proc Natl Acad Sci U S A (2016)

A reversible gene trap collection empowers haploid genetics in human cells

Yazar: Bürckstümmer, Tilmann, Banning, Carina, Hainzl, Philipp, Schobesberger, Richard, Kerzendorfer, Claudia, Pauler, Florian M, Chen, Doris, Them, Nicole, Schischlik, Fiorella, Rebsamen, Manuele, Smida, Michal, de la Cruz, Ferran Fece, Lapao, Ana, Liszt, Melissa, Eizinger, Benjamin, Guenzl, Philipp M, Blomen, Vincent A, Konopka, Tomasz, Gapp, Bianca, Parapatics, Katja, Maier, Barbara, Stöckl, Johannes, Fischl, Wolfgang, Salic, Sejla, Taba Casari, M Rita, Knapp, Sylvia, Bennett, Keiryn L, Bock, Christoph, Colinge, Jacques, Kralovics, Robert, Ammerer, Gustav, Casari, Georg, Brummelkamp, Thijn R, Superti-Furga, Giulio, Nijman, Sebastian M B
Yayımlandı Nat Methods (2013)