A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection

Rift Valley fever virus (RVFV) causes recurrent insect-borne epizootics throughout the African continent, and infection of humans can lead to a lethal hemorrhagic fever syndrome. Deep mutagenesis of haploid human cells was used to identify host factors required for RVFV infection. This screen identi...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Riblett, Amber M., Blomen, Vincent A., Jae, Lucas T., Altamura, Louis A., Doms, Robert W., Brummelkamp, Thijn R., Wojcechowskyj, Jason A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719632/
https://ncbi.nlm.nih.gov/pubmed/26581979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02055-15
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