A Reporter Screen in a Human Haploid Cell Line Identifies CYLD as a Constitutive Inhibitor of NF-κB

Bằng Lee, Clarissa C., Carette, Jan E., Brummelkamp, Thijn R., Ploegh, Hidde L.
Được phát hành 2013

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)–p53 signaling

Bằng Shvarts, Avi, Brummelkamp, Thijn R., Scheeren, Ferenc, Koh, Eugene, Daley, George Q., Spits, Hergen, Bernards, René
Được phát hành 2002

Human Immunodeficiency Virus Type 1 Escapes from RNA Interference-Mediated Inhibition

Bằng Das, Atze T., Brummelkamp, Thijn R., Westerhout, Ellen M., Vink, Monique, Madiredjo, Mandy, Bernards, René, Berkhout, Ben
Được phát hành 2004

A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

Bằng Reiling, Jan H., Clish, Clary B., Carette, Jan E., Varadarajan, Malini, Brummelkamp, Thijn R., Sabatini, David M.
Được phát hành 2011

Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)

Bằng Papatheodorou, Panagiotis, Carette, Jan E., Bell, George W., Schwan, Carsten, Guttenberg, Gregor, Brummelkamp, Thijn R., Aktories, Klaus
Được phát hành 2011

Attachment of Chlamydia trachomatis L2 to host cells requires sulfation

Bằng Rosmarin, David M., Carette, Jan E., Olive, Andrew J., Starnbach, Michael N., Brummelkamp, Thijn R., Ploegh, Hidde L.
Được phát hành 2012

GPR107, a G-protein-coupled Receptor Essential for Intoxication by Pseudomonas aeruginosa Exotoxin A, Localizes to the Golgi and Is Cleaved by Furin

Bằng Tafesse, Fikadu G., Guimaraes, Carla P., Maruyama, Takeshi, Carette, Jan E., Lory, Stephen, Brummelkamp, Thijn R., Ploegh, Hidde L.
Được phát hành 2014

A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection

Bằng Riblett, Amber M., Blomen, Vincent A., Jae, Lucas T., Altamura, Louis A., Doms, Robert W., Brummelkamp, Thijn R., Wojcechowskyj, Jason A.
Xuất bản năm J Virol (2016)

Diverse viruses require the calcium transporter SPCA1 for maturation and spread

Bằng Hoffmann, H.-Heinrich, Schneider, William M, Blomen, Vincent A, Scull, Margaret A, Hovnanian, Alain, Brummelkamp, Thijn R, Rice, Charles M
Xuất bản năm Cell Host Microbe (2017)

Identification of host cell factors required for intoxication through use of modified cholera toxin

Bằng Guimaraes, Carla P., Carette, Jan E., Varadarajan, Malini, Antos, John, Popp, Maximilian W., Spooner, Eric, Brummelkamp, Thijn R., Ploegh, Hidde L.
Được phát hành 2011

Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents

Bằng Gerhards, Nora M., Blomen, Vincent A., Mutlu, Merve, Nieuwenhuis, Joppe, Howald, Denise, Guyader, Charlotte, Jonkers, Jos, Brummelkamp, Thijn R., Rottenberg, Sven
Xuất bản năm Mol Oncol (2018)

SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing

Bằng Mezzadra, Riccardo, de Bruijn, Marjolein, Jae, Lucas T., Gomez-Eerland, Raquel, Duursma, Anja, Scheeren, Ferenc A., Brummelkamp, Thijn R., Schumacher, Ton N.
Xuất bản năm PLoS One (2019)

Generation of iPSCs from cultured human malignant cells

Bằng Carette, Jan E., Pruszak, Jan, Varadarajan, Malini, Blomen, Vincent A., Gokhale, Sumita, Camargo, Fernando D., Wernig, Marius, Jaenisch, Rudolf, Brummelkamp, Thijn R.
Được phát hành 2010

LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins

Bằng Schorch, Björn, Song, Shuo, van Diemen, Ferdy R., Bock, Hans H., May, Petra, Herz, Joachim, Brummelkamp, Thijn R., Papatheodorou, Panagiotis, Aktories, Klaus
Được phát hành 2014

Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line

Bằng Essletzbichler, Patrick, Konopka, Tomasz, Santoro, Federica, Chen, Doris, Gapp, Bianca V., Kralovics, Robert, Brummelkamp, Thijn R., Nijman, Sebastian M.B., Bürckstümmer, Tilmann
Xuất bản năm Genome Res (2014)

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

Bằng Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Xuất bản năm Nat Commun (2019)

A Luman/CREB3–ADP-ribosylation factor 4 (ARF4) signaling pathway mediates the response to Golgi stress and susceptibility to pathogens

Bằng Reiling, Jan H., Olive, Andrew J., Sanyal, Sumana, Carette, Jan E., Brummelkamp, Thijn R., Ploegh, Hidde L., Starnbach, Michael N., Sabatini, David M.
Được phát hành 2013

Yap1 acts downstream of α-catenin to control epidermal proliferation

Bằng Schlegelmilch, Karin, Mohseni, Morvarid, Kirak, Oktay, Pruszak, Jan, Rodriguez, J. Renato, Zhou, Dawang, Kreger, Bridget T., Vasioukhin, Valera, Avruch, Joseph, Brummelkamp, Thijn R., Camargo, Fernando D.
Được phát hành 2011

E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes

Bằng Sarbanes, Stephanie L., Blomen, Vincent A., Lam, Eric, Heissel, Søren, Luna, Joseph M., Brummelkamp, Thijn R., Falck-Pedersen, Erik, Hoffmann, H.-Heinrich, Rice, Charles M.
Xuất bản năm Proc Natl Acad Sci U S A (2021)

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

Bằng Kleinfelter, Lara M., Jangra, Rohit K., Jae, Lucas T., Herbert, Andrew S., Mittler, Eva, Stiles, Katie M., Wirchnianski, Ariel S., Kielian, Margaret, Brummelkamp, Thijn R., Dye, John M., Chandran, Kartik
Xuất bản năm mBio (2015)