Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)

Clostridium difficile infection (CDI) causes antibiotic-associated diarrhea and pseudomembranous colitis. Hypervirulent strains of the pathogen, which are responsible for increased morbidity and mortality of CDI, produce the binary actin-ADP ribosylating toxin Clostridium difficile transferase (CDT)...

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Autores principales: Papatheodorou, Panagiotis, Carette, Jan E., Bell, George W., Schwan, Carsten, Guttenberg, Gregor, Brummelkamp, Thijn R., Aktories, Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182710/
https://ncbi.nlm.nih.gov/pubmed/21930894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109772108
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