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Interaction of the Clostridium difficile Binary Toxin CDT and Its Host Cell Receptor, Lipolysis-stimulated Lipoprotein Receptor (LSR)

CDT (Clostridium difficile transferase) is a binary, actin ADP-ribosylating toxin frequently associated with hypervirulent strains of the human enteric pathogen C. difficile, the most serious cause of antibiotic-associated diarrhea and pseudomembranous colitis. CDT leads to the collapse of the actin...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Hemmasi, Sarah, Czulkies, Bernd A., Schorch, Björn, Veit, Antonia, Aktories, Klaus, Papatheodorou, Panagiotis
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447975/
https://ncbi.nlm.nih.gov/pubmed/25882847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.650523
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