Clostridium difficile Binary Toxin CDT Induces Clustering of the Lipolysis-Stimulated Lipoprotein Receptor into Lipid Rafts

Clostridium difficile is the leading cause of antibiotics-associated diarrhea and pseudomembranous colitis. Hypervirulent C. difficile strains produce the binary actin-ADP-ribosylating toxin CDT (C. difficile transferase), in addition to the Rho-glucosylating toxins A and B. We recently identified t...

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Main Authors: Papatheodorou, Panagiotis, Hornuss, Daniel, Nölke, Thilo, Hemmasi, Sarah, Castonguay, Jan, Picchianti, Monica, Aktories, Klaus
格式: Artigo
語言:Inglês
出版: American Society of Microbiology 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648903/
https://ncbi.nlm.nih.gov/pubmed/23631918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00244-13
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