Tailored Cyclodextrin Pore Blocker Protects Mammalian Cells from Clostridium difficile Binary Toxin CDT

Some Clostridium difficile strains produce, in addition to toxins A and B, the binary toxin Clostridium difficile transferase (CDT), which ADP-ribosylates actin and may contribute to the hypervirulence of these strains. The separate binding and translocation component CDTb mediates transport of the...

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Hlavní autoři: Roeder, Maurice, Nestorovich, Ekaterina M., Karginov, Vladimir A., Schwan, Carsten, Aktories, Klaus, Barth, Holger
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113744/
https://ncbi.nlm.nih.gov/pubmed/25029374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins6072097
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