Diverse viruses require the calcium transporter SPCA1 for maturation and spread

Respiratory and arthropod-borne viral infections are a global threat due to the lack of effective antivirals and vaccines. A potential strategy is to target host proteins required for viruses but non-essential for the host. To identify such proteins, we performed a genome-wide knockout screen in hum...

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Bibliografiska uppgifter
I publikationen:Cell Host Microbe
Huvudupphovsmän: Hoffmann, H.-Heinrich, Schneider, William M, Blomen, Vincent A, Scull, Margaret A, Hovnanian, Alain, Brummelkamp, Thijn R, Rice, Charles M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952603/
https://ncbi.nlm.nih.gov/pubmed/29024641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.09.002
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