SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing

Experimental and clinical observations have highlighted the role of cytotoxic T cells in human tumor control. However, the parameters that control tumor cell sensitivity to T cell attack remain incompletely understood. To identify modulators of tumor cell sensitivity to T cell effector mechanisms, w...

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Udgivet i:PLoS One
Main Authors: Mezzadra, Riccardo, de Bruijn, Marjolein, Jae, Lucas T., Gomez-Eerland, Raquel, Duursma, Anja, Scheeren, Ferenc A., Brummelkamp, Thijn R., Schumacher, Ton N.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372190/
https://ncbi.nlm.nih.gov/pubmed/30753225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212053
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