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IFNγ: Issuing macrophages a license to kill
T cells tell macrophages when to start making the toxic soup of lysosomal enzymes, reactive oxygen species, and nitric oxide that destroys intracellular pathogens. In 1983, Carl Nathan proved that this start signal comes in the form of the secreted cytokine IFNγ.
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2007
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118418/ https://ncbi.nlm.nih.gov/pubmed/17227915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.2041fta |
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