CD29 identifies IFN-γ–producing human CD8(+) T cells with an increased cytotoxic potential

Cytotoxic CD8(+) T cells can effectively kill target cells by producing cytokines, chemokines, and granzymes. Expression of these effector molecules is however highly divergent, and tools that identify and preselect CD8(+) T cells with a cytotoxic expression profile are lacking. Human CD8(+) T cells...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Nicolet, Benoît P., Guislain, Aurélie, van Alphen, Floris P. J., Gomez-Eerland, Raquel, Schumacher, Ton N. M., van den Biggelaar, Maartje, Wolkers, Monika C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104308/
https://ncbi.nlm.nih.gov/pubmed/32161126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913940117
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