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Regulation of IFN-γ Signaling Is Essential for the Cytotoxic Activity of CD8(+) T Cells()

Previous studies have demonstrated that, as naive murine CD4(+) cells differentiate into Th1 cells, they lose expression of the second chain of IFN-γR (IFN-γR2). Hence, the IFN-γ-producing subset of Th cells is unresponsive to IFN-γ. Analysis of IFN-γ-producing CD8(+) T cells demonstrates that, like...

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Bibliografiset tiedot
Julkaisussa:J Immunol
Päätekijät: Tau, Gregory Z., Cowan, Simone N., Weisburg, Jeffrey, Braunstein, Ned S., Rothman, Paul B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2001
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416493/
https://ncbi.nlm.nih.gov/pubmed/11698428
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