LRP1 is a receptor for Clostridium perfringens TpeL toxin indicating a two-receptor model of clostridial glycosylating toxins

Large glycosylating toxins are major virulence factors of various species of pathogenic Clostridia. Prototypes are Clostridium difficile toxins A and B, which cause antibiotics-associated diarrhea and pseudomembranous colitis. The current model of the toxins’ action suggests that receptor binding is...

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Detalhes bibliográficos
Main Authors: Schorch, Björn, Song, Shuo, van Diemen, Ferdy R., Bock, Hans H., May, Petra, Herz, Joachim, Brummelkamp, Thijn R., Papatheodorou, Panagiotis, Aktories, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035940/
https://ncbi.nlm.nih.gov/pubmed/24737893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323790111
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