Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) in the Old World and a highly fatal hantavirus cardiopulmonary syndrome (HCPS) in the New World. No vaccines or antiviral therapies are currently available to prevent or treat hantavirus disease, and gaps in our understanding of how han...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Kleinfelter, Lara M., Jangra, Rohit K., Jae, Lucas T., Herbert, Andrew S., Mittler, Eva, Stiles, Katie M., Wirchnianski, Ariel S., Kielian, Margaret, Brummelkamp, Thijn R., Dye, John M., Chandran, Kartik
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488941/
https://ncbi.nlm.nih.gov/pubmed/26126854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00801-15
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