Protocadherin-1 is essential for cell entry by New World hantaviruses

The zoonotic transmission of hantaviruses from their rodent hosts to humans in North and South America is associated with a severe and frequently fatal respiratory disease, hantavirus pulmonary syndrome (HPS)(1,2). No specific antiviral treatments for HPS are available, and no molecular determinants...

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Publicado en:Nature
Autores principales: Jangra, Rohit K., Herbert, Andrew S., Li, Rong, Jae, Lucas T., Kleinfelter, Lara M., Slough, Megan M., Barker, Sarah L., Guardado-Calvo, Pablo, Román-Sosa, Gleyder, Dieterle, M. Eugenia, Kuehne, Ana I., Muena, Nicolás A., Wirchnianski, Ariel S., Nyakatura, Elisabeth K., Fels, J. Maximilian, Ng, Melinda, Mittler, Eva, Pan, James, Bharrhan, Sushma, Wec, Anna Z., Lai, Jonathan r., Sidhu, Sachdev S., Tischler, Nicole D., rey, Félix A., Moffat, Jason, Brummelkamp, Thijn R., Wang, Zhongde, Dye, John M., Chandran, Kartik
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556216/
https://ncbi.nlm.nih.gov/pubmed/30464266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0702-1
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