Protocadherin-1 is essential for cell entry by New World hantaviruses

The zoonotic transmission of hantaviruses from their rodent hosts to humans in North and South America is associated with a severe and frequently fatal respiratory disease, hantavirus pulmonary syndrome (HPS)(1,2). No specific antiviral treatments for HPS are available, and no molecular determinants...

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Publicat a:Nature
Autors principals: Jangra, Rohit K., Herbert, Andrew S., Li, Rong, Jae, Lucas T., Kleinfelter, Lara M., Slough, Megan M., Barker, Sarah L., Guardado-Calvo, Pablo, Román-Sosa, Gleyder, Dieterle, M. Eugenia, Kuehne, Ana I., Muena, Nicolás A., Wirchnianski, Ariel S., Nyakatura, Elisabeth K., Fels, J. Maximilian, Ng, Melinda, Mittler, Eva, Pan, James, Bharrhan, Sushma, Wec, Anna Z., Lai, Jonathan r., Sidhu, Sachdev S., Tischler, Nicole D., rey, Félix A., Moffat, Jason, Brummelkamp, Thijn R., Wang, Zhongde, Dye, John M., Chandran, Kartik
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556216/
https://ncbi.nlm.nih.gov/pubmed/30464266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0702-1
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