A Luman/CREB3–ADP-ribosylation factor 4 (ARF4) signaling pathway mediates the response to Golgi stress and susceptibility to pathogens

Treatment of cells with Brefeldin A (BFA) blocks secretory vesicle transport and causes a collapse of the Golgi apparatus. To gain more insight into the cellular mechanisms mediating BFA toxicity, we conducted a genome-wide haploid genetic screen that led to the identification of the small G protein...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Reiling, Jan H., Olive, Andrew J., Sanyal, Sumana, Carette, Jan E., Brummelkamp, Thijn R., Ploegh, Hidde L., Starnbach, Michael N., Sabatini, David M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965854/
https://ncbi.nlm.nih.gov/pubmed/24185178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2865
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