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Generation of iPSCs from cultured human malignant cells

Induced pluripotent stem cells (iPSCs) can be generated from various differentiated cell types by the expression of a set of defined transcription factors. So far, iPSCs have been generated from primary cells, but it is unclear whether human cancer cell lines can be reprogrammed. Here we describe th...

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Hlavní autoři: Carette, Jan E., Pruszak, Jan, Varadarajan, Malini, Blomen, Vincent A., Gokhale, Sumita, Camargo, Fernando D., Wernig, Marius, Jaenisch, Rudolf, Brummelkamp, Thijn R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875096/
https://ncbi.nlm.nih.gov/pubmed/20233975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-231845
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