Transgene-free iPSCs generated from small volume peripheral blood nonmobilized CD34(+) cells

A variety of somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs), but CD34(+) hematopoietic stem cells (HSCs) present in nonmobilized peripheral blood (PB) would be a convenient target. We report a method for deriving iPSC from PB HSCs using immunobead purification and 2- to...

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Autori principali: Merling, Randall K., Sweeney, Colin L., Choi, Uimook, De Ravin, Suk See, Myers, Timothy G., Otaizo-Carrasquero, Francisco, Pan, Jason, Linton, Gilda, Chen, Lifeng, Koontz, Sherry, Theobald, Narda L., Malech, Harry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617640/
https://ncbi.nlm.nih.gov/pubmed/23386128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-420273
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