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Molecular analysis of neutrophil differentiation from human iPSCs delineates the kinetics of key regulators of hematopoiesis

In vitro generation of mature neutrophils from human induced pluripotent stem cells (iPSCs) requires hematopoietic progenitor development followed by myeloid differentiation. The purpose of our studies was to extensively characterize this process, focusing on the critical window of development betwe...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Sweeney, Colin L., Teng, Ruifeng, Wang, Hongmei, Merling, Randall K., Lee, Janet, Choi, Uimook, Koontz, Sherry, Wright, Daniel G., Malech, Harry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892955/
https://ncbi.nlm.nih.gov/pubmed/26866427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2332
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