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Molecular analysis of neutrophil differentiation from human iPSCs delineates the kinetics of key regulators of hematopoiesis

In vitro generation of mature neutrophils from human induced pluripotent stem cells (iPSCs) requires hematopoietic progenitor development followed by myeloid differentiation. The purpose of our studies was to extensively characterize this process, focusing on the critical window of development betwe...

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Publicat a:Stem Cells
Autors principals: Sweeney, Colin L., Teng, Ruifeng, Wang, Hongmei, Merling, Randall K., Lee, Janet, Choi, Uimook, Koontz, Sherry, Wright, Daniel G., Malech, Harry L.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892955/
https://ncbi.nlm.nih.gov/pubmed/26866427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2332
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