Heparan Sulfate Facilitates Rift Valley Fever Virus Entry into the Cell

Rift Valley fever virus (RVFV), an emerging arthropod-borne pathogen, has a broad host and cell tropism. Here we report that the glycosaminoglycan heparan sulfate, abundantly present on the surface of most animal cells, is required for efficient entry of RVFV. Entry was significantly reduced by prei...

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Bibliographic Details
Main Authors: de Boer, S. M., Kortekaas, J., de Haan, C. A. M., Rottier, P. J. M., Moormann, R. J. M., Bosch, B. J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503077/
https://ncbi.nlm.nih.gov/pubmed/23015725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01364-12
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