Heparan Sulfate Facilitates Rift Valley Fever Virus Entry into the Cell

Rift Valley fever virus (RVFV), an emerging arthropod-borne pathogen, has a broad host and cell tropism. Here we report that the glycosaminoglycan heparan sulfate, abundantly present on the surface of most animal cells, is required for efficient entry of RVFV. Entry was significantly reduced by prei...

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Main Authors: de Boer, S. M., Kortekaas, J., de Haan, C. A. M., Rottier, P. J. M., Moormann, R. J. M., Bosch, B. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503077/
https://ncbi.nlm.nih.gov/pubmed/23015725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01364-12
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