Vertical pathway inhibition overcomes adaptive feedback resistance to KRAS(G12C) inhibition

per Ryan, Meagan B., de la Cruz, Ferran Fece, Phat, Sarah, Myers, David T., Wong, Edmond, Shahzade, Heather A., Hong, Catriona B., Corcoran, Ryan B.
Publicat a Clin Cancer Res (2019)

A reversible gene trap collection empowers haploid genetics in human cells

per Bürckstümmer, Tilmann, Banning, Carina, Hainzl, Philipp, Schobesberger, Richard, Kerzendorfer, Claudia, Pauler, Florian M, Chen, Doris, Them, Nicole, Schischlik, Fiorella, Rebsamen, Manuele, Smida, Michal, de la Cruz, Ferran Fece, Lapao, Ana, Liszt, Melissa, Eizinger, Benjamin, Guenzl, Philipp M, Blomen, Vincent A, Konopka, Tomasz, Gapp, Bianca, Parapatics, Katja, Maier, Barbara, Stöckl, Johannes, Fischl, Wolfgang, Salic, Sejla, Taba Casari, M Rita, Knapp, Sylvia, Bennett, Keiryn L, Bock, Christoph, Colinge, Jacques, Kralovics, Robert, Ammerer, Gustav, Casari, Georg, Brummelkamp, Thijn R, Superti-Furga, Giulio, Nijman, Sebastian M B
Publicat a Nat Methods (2013)

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma

per Goyal, Lipika, Shi, Lei, Liu, Leah Y., de la Cruz, Ferran Fece, Lennerz, Jochen K., Raghavan, Srivatsan, Leschiner, Ignaty, Elagina, Liudmila, Siravegna, Giulia, Ng, Raymond W.S., Vu, Phuong, Patra, Krushna C., Saha, Supriya K., Uppot, Raul N., Arellano, Ron, Reyes, Stephanie, Sagara, Takeshi, Otsuki, Sachie, Nadres, Brandon, Shahzade, Heather A., Dey-Guha, Ipsita, Fetter, Isobel J., Baiev, Islam, Van Seventer, Emily E., Murphy, Janet E., Ferrone, Cristina R., Tanabe, Kenneth K., Deshpande, Vikram, Harding, James J., Yaeger, Rona, Kelley, Robin K., Bardelli, Alberto, Iafrate, A. John, Hahn, William C., Benes, Cyril H., Ting, David T., Hirai, Hiroshi, Getz, Gad, Juric, Dejan, Zhu, Andrew X., Corcoran, Ryan B., Bardeesy, Nabeel
Publicat a Cancer Discov (2019)

Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers

per Parikh, Aparna R., Leshchiner, Ignaty, Elagina, Liudmila, Goyal, Lipika, Levovitz, Chaya, Siravegna, Giulia, Livitz, Dimitri, Rhrissorrakrai, Kahn, Martin, Elizabeth E., Van Seventer, Emily E., Hanna, Megan, Slowik, Kara, Utro, Filippo, Pinto, Christopher J., Wong, Alicia, Danysh, Brian P., de la Cruz, Ferran Fece, Fetter, Isobel J., Nadres, Brandon, Shahzade, Heather A., Allen, Jill N., Blaszkowsky, Lawrence S., Clark, Jeffrey W., Giantonio, Bruce, Murphy, Janet E., Nipp, Ryan D., Roeland, Eric, Ryan, David P., Weekes, Colin D., Kwak, Eunice L., Faris, Jason E., Wo, Jennifer Y., Aguet, François, Dey-Guha, Ipsita, Hazar-Rethinam, Mehlika, Dias-Santagata, Dora, Ting, David T., Zhu, Andrew X., Hong, Theodore S., Golub, Todd R., Iafrate, A. John, Adalsteinsson, Viktor A., Bardelli, Alberto, Parida, Laxmi, Juric, Dejan, Getz, Gad, Corcoran, Ryan B.
Publicat a Nat Med (2019)