BRAF Mutations in Colorectal Cancer: Clinical Relevance and Role in Targeted Therapy

Por Yaeger, Rona, Saltz, Leonard
Publicado em 2012

Impact of somatic mutations on patterns of metastasis in colorectal cancer

Por Lipsyc, Marla, Yaeger, Rona
Publicado no J Gastrointest Oncol (2015)

Applying tumor genotyping and new clinical approaches to the management of colorectal cancer

Por Yaeger, Rona D., Kemeny, Nancy E.
Publicado no J Gastrointest Oncol (2015)

Immunohistochemical detection of the BRAF V600E mutant protein in colorectal neoplasms

Por Vakiani, Efsevia, Yaeger, Rona, Brooke, Sylvester, Zhou, Yi, Klimstra, David S., Shia, Jinru
Publicado no Appl Immunohistochem Mol Morphol (2015)

AKT1 E17K in Colorectal Carcinoma Is Associated with BRAF V600E but Not MSI-H Status: A Clinicopathologic Comparison to PIK3CA Helical and Kinase Domain Mutants

Por Hechtman, Jaclyn F., Sadowska, Justyna, Huse, Jason T., Borsu, Laetitia, Yaeger, Rona, Shia, Jinru, Vakiani, Efsevia, Ladanyi, Marc, Arcila, Maria E.
Publicado no Mol Cancer Res (2015)

RAS Mutations Affect Pattern of Metastatic Spread and Increase Propensity for Brain Metastasis in Colorectal Cancer

Por Yaeger, Rona, Cowell, Elizabeth, Chou, Joanne F., Gewirtz, Alexandra N., Borsu, Laetitia, Vakiani, Efsevia, Solit, David B., Rosen, Neal, Capanu, Marinela, Ladanyi, Marc, Kemeny, Nancy
Publicado no Cancer (2014)

Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF

Por Hechtman, Jaclyn F., Zehir, Ahmet, Yaeger, Rona, Wang, Lu, Middha, Sumit, Zheng, Tao, Hyman, David M., Solit, David, Arcila, Maria E., Borsu, Laetitia, Shia, Jinru, Vakiani, Efsevia, Saltz, Leonard, Ladanyi, Marc
Publicado no Mol Cancer Res (2015)

Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma

Por Javier, Breanna M., Yaeger, Rona, Wang, Lu, Sanchez-Vega, Francisco, Zehir, Ahmet, Middha, Sumit, Sadowska, Justyna, Vakiani, Efsevia, Shia, Jinru, Klimstra, David, Ladanyi, Marc, Iacobuzio-Donahue, Christine A., Hechtman, Jaclyn F.
Publicado no Oncotarget (2016)

Comparing Genetic Ancestry and Self-Described Race in African Americans Born in the United States and in Africa

Por Yaeger, Rona, Avila-Bront, Alexa, Abdul, Kazeem, Nolan, Patricia C., Grann, Victor R., Birchette, Mark G., Choudhry, Shweta, Burchard, Esteban G., Beckman, Kenneth B., Gorroochurn, Prakash, Ziv, Elad, Consedine, Nathan S., Joe, Andrew K.
Publicado em 2008

BRAF Mutation Predicts for Poor Outcomes After Metastasectomy in Patients With Metastatic Colorectal Cancer

Por Yaeger, Rona, Cercek, Andrea, Chou, Joanne F., Sylvester, Brooke E., Kemeny, Nancy E., Hechtman, Jaclyn F., Ladanyi, Marc, Rosen, Neal, Weiser, Martin R., Capanu, Marinela, Solit, David B., D’Angelica, Michael I., Vakiani, Efsevia, Saltz, Leonard B.
Publicado no Cancer (2014)

Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence

Por Nissan, Moriah H., Pratilas, Christine A., Jones, Alexis M., Ramirez, Ricardo, Won, Helen, Liu, Cailian, Tiwari, Shakuntala, Kong, Li, Hanrahan, Aphrothiti J., Yao, Zhan, Merghoub, Taha, Ribas, Antoni, Chapman, Paul B., Yaeger, Rona, Taylor, Barry S., Schultz, Nikolaus, Berger, Michael F., Rosen, Neal, Solit, David B.
Publicado em 2014

Emergence of KRAS mutations and acquired resistance to anti EGFR therapy in colorectal cancer

Por Misale, Sandra, Yaeger, Rona, Hobor, Sebastijan, Scala, Elisa, Janakiraman, Manickam, Liska, David, Valtorta, Emanuele, Schiavo, Roberta, Buscarino, Michela, Siravegna, Giulia, Bencardino, Katia, Cercek, Andrea, Chen, Chin-Tung, Veronese, Silvio, Zanon, Carlo, Sartore-Bianchi, Andrea, Gambacorta, Marcello, Gallicchio, Margherita, Vakiani, Efsevia, Boscaro, Valentina, Medico, Enzo, Weiser, Martin, Siena, Salvatore, Di Nicolantonio, Federica, Solit, David, Bardelli, Alberto
Publicado em 2012

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

Por Brannon, A Rose, Vakiani, Efsevia, Sylvester, Brooke E, Scott, Sasinya N, McDermott, Gregory, Shah, Ronak H, Kania, Krishan, Viale, Agnes, Oschwald, Dayna M, Vacic, Vladimir, Emde, Anne-Katrin, Cercek, Andrea, Yaeger, Rona, Kemeny, Nancy E, Saltz, Leonard B, Shia, Jinru, D’Angelica, Michael I, Weiser, Martin R, Solit, David B, Berger, Michael F
Publicado em 2014

Reliable Detection of Mismatch Repair Deficiency in Colorectal Cancers Using Mutational Load in Next-Generation Sequencing Panels

Por Stadler, Zsofia K., Battaglin, Francesca, Middha, Sumit, Hechtman, Jaclyn F., Tran, Christina, Cercek, Andrea, Yaeger, Rona, Segal, Neil H., Varghese, Anna M., Reidy-Lagunes, Diane L., Kemeny, Nancy E., Salo-Mullen, Erin E., Ashraf, Asad, Weiser, Martin R., Garcia-Aguilar, Julio, Robson, Mark E., Offit, Kenneth, Arcila, Maria E., Berger, Michael F., Shia, Jinru, Solit, David B., Saltz, Leonard B.
Publicado no J Clin Oncol (2016)

Clinical and genetic determinants of ovarian metastases from colorectal cancer

Por Ganesh, Karuna, Shah, Ronak H., Vakiani, Efsevia, Nash, Garrett M., Skottowe, Hugh P., Yaeger, Rona, Cercek, Andrea, Lincoln, Anne, Tran, Christina, Segal, Neil H., Reidy, Diane L., Varghese, Anna, Epstein, Andrew S., Sonoda, Yukio, Chi, Dennis, Guillem, Jose, Temple, Larissa, Paty, Philip, Hechtman, Jaclyn, Shia, Jinru, Weiser, Martin, Aguilar, Julio Garcia, Kemeny, Nancy, Berger, Michael F., Saltz, Leonard, Stadler, Zsofia K.
Publicado no Cancer (2016)