Tumor evolution and intratumor heterogeneity in colorectal carcinoma: insights from comparative genomic profiling of primary tumors and matched metastases

par Sylvester, Brooke E., Vakiani, Efsevia
Publié dans J Gastrointest Oncol (2015)

Race and Subset Analyses in Clinical Trials: Time to Get Serious About Data Integration

par Polite, Blase N., Sylvester, Brooke E., Olopade, Olufunmilayo I.
Publié 2011

Molecular Analysis of Colorectal Tumors within a Diverse Patient Cohort at a Single Institution

par Sylvester, Brooke E., Huo, Dezheng, Khramtsov, Andrey, Zhang, Jing, Smalling, Rana V., Olugbile, Sope, Polite, Blase N., Olopade, Olufunmilayo I.
Publié 2011

MAP2K1 (MEK1) mutations define a distinct subset of lung adenocarcinoma associated with smoking

par Arcila, Maria E., Drilon, Alexander, Sylvester, Brooke E., Lovly, Christine M., Borsu, Laetitia, Reva, Boris, Kris, Mark G., Solit, David B., Ladanyi, Marc
Publié dans Clin Cancer Res (2014)

3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets

par Gao, Jianjiong, Chang, Matthew T., Johnsen, Hannah C., Gao, Sizhi Paul, Sylvester, Brooke E., Sumer, Selcuk Onur, Zhang, Hongxin, Solit, David B., Taylor, Barry S., Schultz, Nikolaus, Sander, Chris
Publié dans Genome Med (2017)

BRAF Mutation Predicts for Poor Outcomes After Metastasectomy in Patients With Metastatic Colorectal Cancer

par Yaeger, Rona, Cercek, Andrea, Chou, Joanne F., Sylvester, Brooke E., Kemeny, Nancy E., Hechtman, Jaclyn F., Ladanyi, Marc, Rosen, Neal, Weiser, Martin R., Capanu, Marinela, Solit, David B., D’Angelica, Michael I., Vakiani, Efsevia, Saltz, Leonard B.
Publié dans Cancer (2014)

The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon

par Grimm, Wesley A, Messer, Jeannette S, Murphy, Stephen F, Nero, Thomas, Lodolce, James P, Weber, Christopher R, Logsdon, Mark F, Bartulis, Sarah, Sylvester, Brooke E, Springer, Amanda, Dougherty, Urszula, Niewold, Timothy B, Kupfer, Sonia S, Ellis, Nathan, Huo, Dezheng, Bissonnette, Marc, Boone, David L
Publié dans Gut (2016)

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

par Brannon, A Rose, Vakiani, Efsevia, Sylvester, Brooke E, Scott, Sasinya N, McDermott, Gregory, Shah, Ronak H, Kania, Krishan, Viale, Agnes, Oschwald, Dayna M, Vacic, Vladimir, Emde, Anne-Katrin, Cercek, Andrea, Yaeger, Rona, Kemeny, Nancy E, Saltz, Leonard B, Shia, Jinru, D’Angelica, Michael I, Weiser, Martin R, Solit, David B, Berger, Michael F
Publié 2014

Extreme Outlier Analysis Identifies Occult Mitogen-Activated Protein Kinase Pathway Mutations in Patients With Low-Grade Serous Ovarian Cancer

par Grisham, Rachel N., Sylvester, Brooke E., Won, Helen, McDermott, Gregory, DeLair, Deborah, Ramirez, Ricardo, Yao, Zhan, Shen, Ronglai, Dao, Fanny, Bogomolniy, Faina, Makker, Vicky, Sala, Evis, Soumerai, Tara E., Hyman, David M., Socci, Nicholas D., Viale, Agnes, Gershenson, David M., Farley, John, Levine, Douglas A., Rosen, Neal, Berger, Michael F., Spriggs, David R., Aghajanian, Carol A., Solit, David B., Iyer, Gopa
Publié dans J Clin Oncol (2015)

Leveraging systematic functional analysis to benchmark an in silico framework distinguishes driver from passenger MEK mutants in cancer

par Hanrahan, Aphrothiti J., Sylvester, Brooke E., Chang, Matthew T., Elzein, Arijh, Gao, JianJiong, Han, Weiwei, Liu, Ye, Xu, Dong, Gao, Sizhi P., Gorelick, Alexander N., Jones, Alexis M., Kiliti, Amber J., Nissan, Moriah H., Nimura, Clare A., Poteshman, Abigail N., Yao, Zhan, Gao, Yijun, Hu, Wenhuo, Wise, Hannah C., Gavrila, Elena I., Shoushtari, Alexander N., Tiwari, Shakuntala, Viale, Agnes, Abdel-Wahab, Omar, Merghoub, Taha, Berger, Michael F., Rosen, Neal, Taylor, Barry S., Solit, David B.
Publié dans Cancer Res (2020)