Tumor evolution and intratumor heterogeneity in colorectal carcinoma: insights from comparative genomic profiling of primary tumors and matched metastases

Por Sylvester, Brooke E., Vakiani, Efsevia
Publicado no J Gastrointest Oncol (2015)

Race and Subset Analyses in Clinical Trials: Time to Get Serious About Data Integration

Por Polite, Blase N., Sylvester, Brooke E., Olopade, Olufunmilayo I.
Publicado em 2011

Molecular Analysis of Colorectal Tumors within a Diverse Patient Cohort at a Single Institution

Por Sylvester, Brooke E., Huo, Dezheng, Khramtsov, Andrey, Zhang, Jing, Smalling, Rana V., Olugbile, Sope, Polite, Blase N., Olopade, Olufunmilayo I.
Publicado em 2011

MAP2K1 (MEK1) mutations define a distinct subset of lung adenocarcinoma associated with smoking

Por Arcila, Maria E., Drilon, Alexander, Sylvester, Brooke E., Lovly, Christine M., Borsu, Laetitia, Reva, Boris, Kris, Mark G., Solit, David B., Ladanyi, Marc
Publicado no Clin Cancer Res (2014)

3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets

Por Gao, Jianjiong, Chang, Matthew T., Johnsen, Hannah C., Gao, Sizhi Paul, Sylvester, Brooke E., Sumer, Selcuk Onur, Zhang, Hongxin, Solit, David B., Taylor, Barry S., Schultz, Nikolaus, Sander, Chris
Publicado no Genome Med (2017)

BRAF Mutation Predicts for Poor Outcomes After Metastasectomy in Patients With Metastatic Colorectal Cancer

Por Yaeger, Rona, Cercek, Andrea, Chou, Joanne F., Sylvester, Brooke E., Kemeny, Nancy E., Hechtman, Jaclyn F., Ladanyi, Marc, Rosen, Neal, Weiser, Martin R., Capanu, Marinela, Solit, David B., D’Angelica, Michael I., Vakiani, Efsevia, Saltz, Leonard B.
Publicado no Cancer (2014)

The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon

Por Grimm, Wesley A, Messer, Jeannette S, Murphy, Stephen F, Nero, Thomas, Lodolce, James P, Weber, Christopher R, Logsdon, Mark F, Bartulis, Sarah, Sylvester, Brooke E, Springer, Amanda, Dougherty, Urszula, Niewold, Timothy B, Kupfer, Sonia S, Ellis, Nathan, Huo, Dezheng, Bissonnette, Marc, Boone, David L
Publicado no Gut (2016)

Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

Por Brannon, A Rose, Vakiani, Efsevia, Sylvester, Brooke E, Scott, Sasinya N, McDermott, Gregory, Shah, Ronak H, Kania, Krishan, Viale, Agnes, Oschwald, Dayna M, Vacic, Vladimir, Emde, Anne-Katrin, Cercek, Andrea, Yaeger, Rona, Kemeny, Nancy E, Saltz, Leonard B, Shia, Jinru, D’Angelica, Michael I, Weiser, Martin R, Solit, David B, Berger, Michael F
Publicado em 2014

Extreme Outlier Analysis Identifies Occult Mitogen-Activated Protein Kinase Pathway Mutations in Patients With Low-Grade Serous Ovarian Cancer

Por Grisham, Rachel N., Sylvester, Brooke E., Won, Helen, McDermott, Gregory, DeLair, Deborah, Ramirez, Ricardo, Yao, Zhan, Shen, Ronglai, Dao, Fanny, Bogomolniy, Faina, Makker, Vicky, Sala, Evis, Soumerai, Tara E., Hyman, David M., Socci, Nicholas D., Viale, Agnes, Gershenson, David M., Farley, John, Levine, Douglas A., Rosen, Neal, Berger, Michael F., Spriggs, David R., Aghajanian, Carol A., Solit, David B., Iyer, Gopa
Publicado no J Clin Oncol (2015)