BRAF Mutation Predicts for Poor Outcomes After Metastasectomy in Patients With Metastatic Colorectal Cancer

BACKGROUND: BRAF mutations occur in 5% to 11% of patients with metastatic colorectal cancer (mCRC) and have been associated with poor prognosis. The current study was undertaken to determine the clinicopathologic characteristics, PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subu...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Yaeger, Rona, Cercek, Andrea, Chou, Joanne F., Sylvester, Brooke E., Kemeny, Nancy E., Hechtman, Jaclyn F., Ladanyi, Marc, Rosen, Neal, Weiser, Martin R., Capanu, Marinela, Solit, David B., D’Angelica, Michael I., Vakiani, Efsevia, Saltz, Leonard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928876/
https://ncbi.nlm.nih.gov/pubmed/24737664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28729
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