BRAF Mutation Predicts for Poor Outcomes After Metastasectomy in Patients With Metastatic Colorectal Cancer

BACKGROUND: BRAF mutations occur in 5% to 11% of patients with metastatic colorectal cancer (mCRC) and have been associated with poor prognosis. The current study was undertaken to determine the clinicopathologic characteristics, PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subu...

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Publicado en:Cancer
Autores principales: Yaeger, Rona, Cercek, Andrea, Chou, Joanne F., Sylvester, Brooke E., Kemeny, Nancy E., Hechtman, Jaclyn F., Ladanyi, Marc, Rosen, Neal, Weiser, Martin R., Capanu, Marinela, Solit, David B., D’Angelica, Michael I., Vakiani, Efsevia, Saltz, Leonard B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928876/
https://ncbi.nlm.nih.gov/pubmed/24737664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28729
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