Pilot Trial of Combined BRAF and EGFR Inhibition in BRAF Mutant Metastatic Colorectal Cancer Patients

PURPOSE: BRAF mutant metastatic colorectal cancer (mCRC) forms an aggressive subset of colorectal cancer with minimal response to selective RAF inhibitors. Preclinical data show that reactivation of epidermal growth factor receptor (EGFR) signaling occurs in colorectal tumor cells treated with RAF i...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Yaeger, Rona, Cercek, Andrea, O'Reilly, Eileen M., Reidy, Diane L., Kemeny, Nancy, Wolinsky, Tamar, Capanu, Marinela, Gollub, Marc J., Rosen, Neal, Berger, Michael F., Lacouture, Mario E., Vakiani, Efsevia, Saltz, Leonard
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546416/
https://ncbi.nlm.nih.gov/pubmed/25589621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2779
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker