A reversible gene trap collection empowers haploid genetics in human cells

Knockout collections are invaluable tools for studying model organisms such as yeast. However, there are no large-scale knockout collections of human cells. Using gene-trap mutagenesis in near-haploid human cells, we established a platform to generate and isolate individual ‘gene-trapped cells’ and...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Nat Methods
Κύριοι συγγραφείς: Bürckstümmer, Tilmann, Banning, Carina, Hainzl, Philipp, Schobesberger, Richard, Kerzendorfer, Claudia, Pauler, Florian M, Chen, Doris, Them, Nicole, Schischlik, Fiorella, Rebsamen, Manuele, Smida, Michal, de la Cruz, Ferran Fece, Lapao, Ana, Liszt, Melissa, Eizinger, Benjamin, Guenzl, Philipp M, Blomen, Vincent A, Konopka, Tomasz, Gapp, Bianca, Parapatics, Katja, Maier, Barbara, Stöckl, Johannes, Fischl, Wolfgang, Salic, Sejla, Taba Casari, M Rita, Knapp, Sylvia, Bennett, Keiryn L, Bock, Christoph, Colinge, Jacques, Kralovics, Robert, Ammerer, Gustav, Casari, Georg, Brummelkamp, Thijn R, Superti-Furga, Giulio, Nijman, Sebastian M B
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2013
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342250/
https://ncbi.nlm.nih.gov/pubmed/24161985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2609
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