Identification of potential immunotherapeutic targets in antigen presentation and costimulation networks

par Spaapen, Robbert, Blomen, Vincent, van Veelen, Peter, Jongsma, Marlieke, Janssen, Lennert, Janssen, George, Raaben, Matthijs, Brummelkamp, Thijn, Neefjes, Jacques
Publié dans J Immunother Cancer (2014)

A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection

par Riblett, Amber M., Blomen, Vincent A., Jae, Lucas T., Altamura, Louis A., Doms, Robert W., Brummelkamp, Thijn R., Wojcechowskyj, Jason A.
Publié dans J Virol (2016)

Diverse viruses require the calcium transporter SPCA1 for maturation and spread

par Hoffmann, H.-Heinrich, Schneider, William M, Blomen, Vincent A, Scull, Margaret A, Hovnanian, Alain, Brummelkamp, Thijn R, Rice, Charles M
Publié dans Cell Host Microbe (2017)

Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents

par Gerhards, Nora M., Blomen, Vincent A., Mutlu, Merve, Nieuwenhuis, Joppe, Howald, Denise, Guyader, Charlotte, Jonkers, Jos, Brummelkamp, Thijn R., Rottenberg, Sven
Publié dans Mol Oncol (2018)

Generation of iPSCs from cultured human malignant cells

par Carette, Jan E., Pruszak, Jan, Varadarajan, Malini, Blomen, Vincent A., Gokhale, Sumita, Camargo, Fernando D., Wernig, Marius, Jaenisch, Rudolf, Brummelkamp, Thijn R.
Publié 2010

A haploid genetic screen identifies the G(1)/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity

par Heijink, Anne Margriet, Blomen, Vincent A., Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel A. T. M.
Publié dans Proc Natl Acad Sci U S A (2015)

E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes

par Sarbanes, Stephanie L., Blomen, Vincent A., Lam, Eric, Heissel, Søren, Luna, Joseph M., Brummelkamp, Thijn R., Falck-Pedersen, Erik, Hoffmann, H.-Heinrich, Rice, Charles M.
Publié dans Proc Natl Acad Sci U S A (2021)

NRP2 and CD63 are host factors for Lujo virus cell entry

par Raaben, Matthijs, Jae, Lucas T., Herbert, Andrew S., Kuehne, Ana I., Stubbs, Sarah H., Chou, Yi-ying, Blomen, Vincent A., Kirchhausen, Tomas, Dye, John M., Brummelkamp, Thijn R., Whelan, Sean P.
Publié dans Cell Host Microbe (2017)

Global gene disruption in human cells to assign genes to phenotypes

par Carette, Jan E., Guimaraes, Carla P., Wuethrich, Irene, Blomen, Vincent A., Varadarajan, Malini, Sun, Chong, Bell, George, Yuan, Bingbing, Muellner, Markus K., Nijman, Sebastian M., Ploegh, Hidde L., Brummelkamp, Thijn R.
Publié 2011

A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection

par Luteijn, Rutger D., van Diemen, Ferdy, Blomen, Vincent A., Boer, Ingrid G. J., Manikam Sadasivam, Saravanan, van Kuppevelt, Toin H., Drexler, Ingo, Brummelkamp, Thijn R., Lebbink, Robert Jan, Wiertz, Emmanuel J.
Publié dans J Virol (2019)

Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants

par Jacobson, Lee S., Lima, Heriberto, Goldberg, Michael F., Gocheva, Vasilena, Tsiperson, Vladislav, Sutterwala, Fayyaz S., Joyce, Johanna A., Gapp, Bianca V., Blomen, Vincent A., Chandran, Kartik, Brummelkamp, Thijn R., Diaz-Griffero, Felipe, Brojatsch, Jürgen
Publié 2013

Deciphering the Glycosylome of Dystroglycanopathies Using Haploid Screens for Lassa Virus Entry

par Jae, Lucas T., Raaben, Matthijs, Riemersma, Moniek, van Beusekom, Ellen, Blomen, Vincent A., Velds, Arno, Kerkhoven, Ron. M., Carette, Jan E., Topaloglu, Haluk, Meinecke, Peter, Wessels, Marja W., Lefeber, Dirk J., Whelan, Sean P., van Bokhoven, Hans, Brummelkamp, Thijn R.
Publié 2013

The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity

par Winter, Georg E., Radic, Branka, Mayor-Ruiz, Cristina, Blomen, Vincent A, Trefzer, Claudia, Kandasamy, Richard K., Huber, Kilian V.M., Gridling, Manuela, Chen, Doris, Klampfl, Thorsten, Kralovics, Robert, Kubicek, Stefan, Fernandez-Capetillo, Oscar, Brummelkamp, Thijn R., Superti-Furga, Giulio
Publié dans Nat Chem Biol (2014)

The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension

par Haarhuis, Judith H.I., van der Weide, Robin H., Blomen, Vincent A., Yáñez-Cuna, J. Omar, Amendola, Mario, van Ruiten, Marjon S., Krijger, Peter H.L., Teunissen, Hans, Medema, René H., van Steensel, Bas, Brummelkamp, Thijn R., de Wit, Elzo, Rowland, Benjamin D.
Publié dans Cell (2017)

Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt‐based anti‐cancer drugs

par Planells‐Cases, Rosa, Lutter, Darius, Guyader, Charlotte, Gerhards, Nora M, Ullrich, Florian, Elger, Deborah A, Kucukosmanoglu, Asli, Xu, Guotai, Voss, Felizia K, Reincke, S Momsen, Stauber, Tobias, Blomen, Vincent A, Vis, Daniel J, Wessels, Lodewyk F, Brummelkamp, Thijn R, Borst, Piet, Rottenberg, Sven, Jentsch, Thomas J
Publié dans EMBO J (2015)

LZTR1 is a regulator of RAS ubiquitination and signaling

par Bigenzahn, Johannes W., Collu, Giovanna M., Kartnig, Felix, Pieraks, Melanie, Vladimer, Gregory I., Heinz, Leonhard X., Sedlyarov, Vitaly, Schischlik, Fiorella, Fauster, Astrid, Rebsamen, Manuele, Parapatics, Katja, Blomen, Vincent A., Müller, André C., Winter, Georg E., Kralovics, Robert, Brummelkamp, Thijn R., Mlodzik, Marek, Superti-Furga, Giulio
Publié dans Science (2018)

Enterovirus D68 receptor requirements unveiled by haploid genetics

par Baggen, Jim, Thibaut, Hendrik Jan, Staring, Jacqueline, Jae, Lucas T., Liu, Yue, Guo, Hongbo, Slager, Jasper J., de Bruin, Jost W., van Vliet, Arno L. W., Blomen, Vincent A., Overduin, Pieter, Sheng, Ju, de Haan, Cornelis A. M., de Vries, Erik, Meijer, Adam, Rossmann, Michael G., Brummelkamp, Thijn R., van Kuppeveld, Frank J. M.
Publié dans Proc Natl Acad Sci U S A (2016)

A reversible gene trap collection empowers haploid genetics in human cells

par Bürckstümmer, Tilmann, Banning, Carina, Hainzl, Philipp, Schobesberger, Richard, Kerzendorfer, Claudia, Pauler, Florian M, Chen, Doris, Them, Nicole, Schischlik, Fiorella, Rebsamen, Manuele, Smida, Michal, de la Cruz, Ferran Fece, Lapao, Ana, Liszt, Melissa, Eizinger, Benjamin, Guenzl, Philipp M, Blomen, Vincent A, Konopka, Tomasz, Gapp, Bianca, Parapatics, Katja, Maier, Barbara, Stöckl, Johannes, Fischl, Wolfgang, Salic, Sejla, Taba Casari, M Rita, Knapp, Sylvia, Bennett, Keiryn L, Bock, Christoph, Colinge, Jacques, Kralovics, Robert, Ammerer, Gustav, Casari, Georg, Brummelkamp, Thijn R, Superti-Furga, Giulio, Nijman, Sebastian M B
Publié dans Nat Methods (2013)