Spy1/SpeedyA accelerates neuroblastoma

door Bisteau, Xavier, Kaldis, Philipp
Gepubliceerd in 2014

The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations

door Bisteau, Xavier, Caldez, Matias J., Kaldis, Philipp
Gepubliceerd in 2014

Differential Regulation of Cyclin-Dependent Kinase 4 (CDK4) and CDK6, Evidence that CDK4 Might Not Be Activated by CDK7, and Design of a CDK6 Activating Mutation

door Bockstaele, Laurence, Bisteau, Xavier, Paternot, Sabine, Roger, Pierre P.
Gepubliceerd in 2009

The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes

door Paternot, Sabine, Colleoni, Bianca, Bisteau, Xavier, Roger, Pierre P
Gepubliceerd in Cell Cycle (2014)

PER2 Circadian Oscillation Sensitizes Esophageal Cancer Cells to Chemotherapy

door Redondo, Juan Alfonso, Bibes, Romain, Vercauteren Drubbel, Alizée, Dassy, Benjamin, Bisteau, Xavier, Maury, Eleonore, Beck, Benjamin
Gepubliceerd in Biology (Basel) (2021)

Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress

door Jayapal, Senthil Raja, Wang, Chelsia Qiuxia, Bisteau, Xavier, Caldez, Matias J., Lim, Shuhui, Tergaonkar, Vinay, Osato, Motomi, Kaldis, Philipp
Gepubliceerd in Haematologica (2015)

Loss of the Greatwall Kinase Weakens the Spindle Assembly Checkpoint

door Diril, M. Kasim, Bisteau, Xavier, Kitagawa, Mayumi, Caldez, Matias J., Wee, Sheena, Gunaratne, Jayantha, Lee, Sang Hyun, Kaldis, Philipp
Gepubliceerd in PLoS Genet (2016)

CDK4 T172 Phosphorylation Is Central in a CDK7-Dependent Bidirectional CDK4/CDK2 Interplay Mediated by p21 Phosphorylation at the Restriction Point

door Bisteau, Xavier, Paternot, Sabine, Colleoni, Bianca, Ecker, Karin, Coulonval, Katia, De Groote, Philippe, Declercq, Wim, Hengst, Ludger, Roger, Pierre P.
Gepubliceerd in 2013

Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary β-Cell Dysfunction to Progressive Depletion of β-Cell Mass and Diabetes

door Kim, So Yoon, Lee, Ji-Hyeon, Merrins, Matthew J., Gavrilova, Oksana, Bisteau, Xavier, Kaldis, Philipp, Satin, Leslie S., Rane, Sushil G.
Gepubliceerd in J Biol Chem (2017)

A haploid genetic screen identifies the G(1)/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity

door Heijink, Anne Margriet, Blomen, Vincent A., Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel A. T. M.
Gepubliceerd in Proc Natl Acad Sci U S A (2015)

Loss of hepatocyte cell division leads to liver inflammation and fibrosis

door Dewhurst, Matthew R., Ow, Jin Rong, Zafer, Gözde, van Hul, Noémi K. M., Wollmann, Heike, Bisteau, Xavier, Brough, David, Choi, Hyungwon, Kaldis, Philipp
Gepubliceerd in PLoS Genet (2020)

Cyclin A2 regulates erythrocyte morphology and numbers

door Jayapal, Senthil Raja, Ang, Heather Yin-Kuan, Wang, Chelsia Qiuxia, Bisteau, Xavier, Caldez, Matias J., Xuan, Gan Xiao, Yu, Weimiao, Tergaonkar, Vinay, Osato, Motomi, Lim, Bing, Kaldis, Philipp
Gepubliceerd in Cell Cycle (2016)

Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

door Szmyd, Radoslaw, Niska-Blakie, Joanna, Diril, M. Kasim, Renck Nunes, Patrícia, Tzelepis, Konstantinos, Lacroix, Aurélie, van Hul, Noémi, Deng, Lih-Wen, Matos, Joao, Dreesen, Oliver, Bisteau, Xavier, Kaldis, Philipp
Gepubliceerd in Oncogene (2018)

Correction: Premature activation of Cdk1 leads to mitotic events in S phase and embryonic lethality

door Szmyd, Radoslaw, Niska-Blakie, Joanna, Diril, M. Kasim, Nunes, Patrícia Renck, Tzelepis, Konstantinos, Lacroix, Aurélie, van Hul, Noémi, Deng, Lih-Wen, Matos, Joao, Dreesen, Oliver, Bisteau, Xavier, Kaldis, Philipp
Gepubliceerd in Oncogene (2019)

Cdk2 catalytic activity is essential for meiotic cell division in vivo

door Chauhan, Sangeeta, Diril, M. Kasim, Lee, Joanna H.S., Bisteau, Xavier, Manoharan, Vanessa, Adhikari, Deepak, Ratnacaram, Chandrahas Koumar, Janela, Baptiste, Noffke, Juliane, Ginhoux, Florent, Coppola, Vincenzo, Liu, Kui, Tessarollo, Lino, Kaldis, Philipp
Gepubliceerd in Biochem J (2016)

CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I

door Palmer, Nathan, Talib, S. Zakiah A., Ratnacaram, Chandrahas Koumar, Low, Diana, Bisteau, Xavier, Lee, Joanna Hui Si, Pfeiffenberger, Elisabeth, Wollmann, Heike, Tan, Joel Heng Loong, Wee, Sheena, Sobota, Radoslaw, Gunaratne, Jayantha, Messerschmidt, Daniel M., Guccione, Ernesto, Kaldis, Philipp
Gepubliceerd in J Cell Biol (2019)

The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis

door Bisteau, Xavier, Lee, Joann, Srinivas, Vinayaka, Lee, Joanna H. S., Niska-Blakie, Joanna, Tan, Gifford, Yap, Shannon Y. X., Hom, Kevin W., Wong, Cheng Kit, Chae, Jeongjun, Wang, Loo Chien, Kim, Jinho, Rancati, Giulia, Sobota, Radoslaw M., Tan, Chris S. H., Kaldis, Philipp
Gepubliceerd in Oncogene (2020)

CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays

door Windpassinger, Christian, Piard, Juliette, Bonnard, Carine, Alfadhel, Majid, Lim, Shuhui, Bisteau, Xavier, Blouin, Stéphane, Ali, Nur’Ain B., Ng, Alvin Yu Jin, Lu, Hao, Tohari, Sumanty, Talib, S. Zakiah A., van Hul, Noémi, Caldez, Matias J., Van Maldergem, Lionel, Yigit, Gökhan, Kayserili, Hülya, Youssef, Sameh A., Coppola, Vincenzo, de Bruin, Alain, Tessarollo, Lino, Choi, Hyungwon, Rupp, Verena, Roetzer, Katharina, Roschger, Paul, Klaushofer, Klaus, Altmüller, Janine, Roy, Sudipto, Venkatesh, Byrappa, Ganger, Rudolf, Grill, Franz, Ben Chehida, Farid, Wollnik, Bernd, Altunoglu, Umut, Al Kaissi, Ali, Reversade, Bruno, Kaldis, Philipp
Gepubliceerd in Am J Hum Genet (2017)