Loss of hepatocyte cell division leads to liver inflammation and fibrosis

The liver possesses a remarkable regenerative capacity based partly on the ability of hepatocytes to re-enter the cell cycle and divide to replace damaged cells. This capability is substantially reduced upon chronic damage, but it is not clear if this is a cause or consequence of liver disease. Here...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Dewhurst, Matthew R., Ow, Jin Rong, Zafer, Gözde, van Hul, Noémi K. M., Wollmann, Heike, Bisteau, Xavier, Brough, David, Choi, Hyungwon, Kaldis, Philipp
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7641358/
https://ncbi.nlm.nih.gov/pubmed/33147210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009084
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