p-Tolyl 2-O-benzoyl-3-O-benzyl-4,6-O-benzyl­idene-1-thio-α-l-idopyran­oside

Por Gainsford, Graeme J., Tyler, Peter C., Zubkova, Olga V.
Publicado em 2010

Thermodynamic Analysis of Transition State Features in Picomolar Inhibitors of Human 5′ Methylthioadenosine Phosphorylase

Por Guan, Rong, Tyler, Peter C., Evans, Gary B., Schramm, Vern L.
Publicado em 2013

Crystal packing in three related disaccharides: precursors to heparan sulfate oligosaccharides

Por Gainsford, Graeme J., Schwörer, Ralf, Tyler, Peter C., Zubkova, Olga V.
Publicado no Acta Crystallogr E Crystallogr Commun (2015)

Transition State Analogues Rescue Ribosomes from Saporin-L1 Ribosome Inactivating Protein

Por Sturm, Matthew B., Tyler, Peter C., Evans, Gary B., Schramm, Vern L.
Publicado em 2009

Synthesis of 5′-Methylthio Coformycins: Specific Inhibitors for Malarial Adenosine Deaminase

Por Tyler, Peter C., Taylor, Erika A., Fröhlich, Richard F. G., Schramm, Vern L.
Publicado em 2007

Immucillins in Custom Catalytic-Site Cavities

Por Murkin, Andrew S., Clinch, Keith, Mason, Jennifer M., Tyler, Peter C., Schramm, Vern L.
Publicado em 2008

A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxyl­ato-1-(9-deaza­adenin-9-yl)-1,4-dide­oxy-1,4-imino-d-ribitol, a member of the ’immucilli...

Por Gainsford, Graeme J., Furneaux, Richard H., Tyler, Peter C., Sauve, Anthony, Shramm, Vern L.
Publicado em 2010

Oligonucleotide transition state analogues of saporin L3

Por Mason, Jennifer M., Yuan, Hongling, Evans, Gary B., Tyler, Peter C., Du, Quan, Schramm, Vern L.
Publicado no Eur J Med Chem (2016)

Altered Enthalpy-Entropy Compensation in Picomolar Transition State Analogues of Human Purine Nucleoside Phosphorylase

Por Edwards, Achelle A., Mason, Jennifer M., Clinch, Keith, Tyler, Peter C., Evans, Gary B., Schramm, Vern L.
Publicado em 2009

Salmonella enterica MTAN at 1.36 Å resolution. Structure-based design of new transition state analogues

Por Haapalainen, Antti M., Thomas, Keisha, Tyler, Peter C., Evans, Gary B., Almo, Steven C., Schramm, Vern L.
Publicado em 2013

Design and Synthesis of Potent “Sulfur-free” Transition State Analogue Inhibitors of 5′-Methylthioadenosine Nucleosidase and 5′-Methylthioadenosine Phosphorylase

Por Longshaw, Alistair I., Adanitsch, Florian, Gutierrez, Jemy A., Evans, Gary B., Tyler, Peter C., Schramm, Vern L.
Publicado em 2010

Continuous Fluorescence Assays for Reactions Involving Adenine

Por Firestone, Ross S., Cameron, Scott A., Tyler, Peter C., Ducati, Rodrigo G., Spitz, Adam Z., Schramm, Vern L.
Publicado no Anal Chem (2016)

Transition State Analogue Discrimination by Related Purine Nucleoside Phosphorylases

Por Taylor Ringia, Erika A., Tyler, Peter C., Evans, Gary B., Furneaux, Richard H., Murkin, Andrew S., Schramm, Vern L.
Publicado em 2006

Methylthioadenosine Deaminase in an Alternative Quorum Sensing Pathway in Pseudomonas aeruginosa

Por Guan, Rong, Ho, Meng-Chiao, Frohlich, Richard F.G., Tyler, Peter C., Almo, Steven C., Schramm, Vern L.
Publicado em 2012

Entropy-Driven Binding of Picomolar Transition State Analogue Inhibitors to Human 5′-Methylthioadenosine Phosphorylase()

Por Guan, Rong, Ho, Meng-Chiao, Brenowitz, Michael, Tyler, Peter C., Evans, Gary B., Almo, Steven C., Schramm, Vern L.
Publicado em 2011

Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase

Por Clinch, Keith, Crump, Douglas R., Evans, Gary B., Hazleton, Keith Z., Mason, Jennifer M., Schramm, Vern L., Tyler, Peter C.
Publicado em 2013

Tight binding enantiomers of pre-clinical drug candidates

Por Evans, Gary B., Cameron, Scott A., Luxenburger, Andreas, Guan, Rong, Suarez, Javier, Thomas, Keisha, Schramm, Vern L., Tyler, Peter C.
Publicado no Bioorg Med Chem (2015)

Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes

Por Kicska, Greg A., Long, Li, Hörig, Heidi, Fairchild, Craig, Tyler, Peter C., Furneaux, Richard H., Schramm, Vern L., Kaufman, Howard L.
Publicado em 2001

Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae

Por Singh, Vipender, Shi, Wuxian, Almo, Steven C., Evans, Gary B., Furneaux, Richard H., Tyler, Peter C., Zheng, Renjian, Schramm, Vern L.
Publicado em 2006

Four generations of transition-state analogues for human purine nucleoside phosphorylase

Por Ho, Meng-Chiao, Shi, Wuxian, Rinaldo-Matthis, Agnes, Tyler, Peter C., Evans, Gary B., Clinch, Keith, Almo, Steven C., Schramm, Vern L.
Publicado em 2010