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Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae
Streptococcus pneumoniae 5′-methylthioadenosine/S-adenosylhomocysteine hydrolase (MTAN) catalyzes the hydrolytic deadenylation of its substrates to form adenine and 5-methylthioribose or S-ribosylhomocysteine (SRH). MTAN is not found in mammals but is involved in bacterial quorum sensing. MTAN gene...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517848/ https://ncbi.nlm.nih.gov/pubmed/17059210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061184i |
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