Binding Isotope Effects: Boon and Bane

Por Schramm, Vern L.
Publicado em 2007

Transition States

Por Schramm, Vern L.
Publicado em 2009

Transition States, Analogues and Drug Development

Por Schramm, Vern L.
Publicado em 2013

Transition States and Transition State Analogue Interactions with Enzymes

Por Schramm, Vern L.
Publicado no Acc Chem Res (2015)

Enzymatic Transition States, Transition-State Analogs, Dynamics, Thermodynamics, and Lifetimes

Por Schramm, Vern L.
Publicado no Annu Rev Biochem (2011)

Enzymatic Transition States and Drug Design

Por Schramm, Vern L.
Publicado no Chem Rev (2018)

Transition State Analysis of S. pneumoniae 5′-Methylthioadenosine Nucleosidase

Por Singh, Vipender, Schramm, Vern L.
Publicado em 2007

Transition state structure of human 5′-methylthioadenosine phosphorylase

Por Singh, Vipender, Schramm, Vern L.
Publicado em 2006

Weak Coupling of ATP Hydrolysis to the Chemical Equilibrium of Human Nicotinamide Phosphoribosyltransferase

Por Burgos, Emmanuel S, Schramm, Vern L.
Publicado em 2008

Pyrophosphate Interactions at the Transition States of Plasmodium falciparum and Human Orotate Phosphoribosyltransferases

Por Zhang, Yong, Schramm, Vern L.
Publicado em 2010

Ground-State Destabilization in Orotate Phosphoribosyltransferases by Binding Isotope Effects

Por Zhang, Yong, Schramm, Vern L.
Publicado em 2011

Isotope-specific and amino acid-specific heavy atom substitutions alter barrier crossing in human purine nucleoside phosphorylase

Por Suarez, Javier, Schramm, Vern L.
Publicado no Proc Natl Acad Sci U S A (2015)

The Transition-State Structure for Human MAT2A from Isotope Effects

Por Firestone, Ross S., Schramm, Vern L.
Publicado no J Am Chem Soc (2017)

Detecting Ricin: A Sensitive Luminescent Assay for Ricin A-chain Ribosome Depurination Kinetics

Por Sturm, Matthew B., Schramm, Vern L.
Publicado em 2009

Enzymatic transition states and dynamic motion in barrier crossing

Por Schwartz, Steven D., Schramm, Vern L.
Publicado em 2009

Uridine phosphorylase from Trypanosoma cruzi: kinetic and chemical mechanisms()

Por Silva, Rafael G., Schramm, Vern L.
Publicado em 2011

Immucillin-H, a purine nucleoside phosphorylase transition state analog, causes non-lethal attenuation of growth in Staphylococcus aureus

Por Stratton, Christopher F, Schramm, Vern L
Publicado em 2013

Promoting Vibrations and the Function of Enzymes. Emerging Theoretical and Experimental Convergence

Por Schramm, Vern L., Schwartz, Steven D.
Publicado no Biochemistry (2018)

Transition States of Plasmodium falciparum and Human Orotate Phosphoribosyltransferases

Por Zhang, Yong, Luo, Minkui, Schramm, Vern L.
Publicado em 2009

Ribocation Transition State Capture and Rebound in Human Purine Nucleoside Phosphorylase

Por Ghanem, Mahmoud, Murkin, Andrew S., Schramm, Vern L.
Publicado em 2009