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Transition States and Transition State Analogue Interactions with Enzymes
Enzymatic transition states have lifetimes of a few femtoseconds (fs). Computational analysis of enzyme motions leading to transition state formation suggests that local catalytic site motions on the fs time scale provide the mechanism to locate transition states. An experimental test of protein fs...
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| Publicado no: | Acc Chem Res |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4482137/ https://ncbi.nlm.nih.gov/pubmed/25848811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.5b00002 |
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