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Transition-State Analogues of Phenylethanolamine N-Methyltransferase

Phenylethanolamine N-methyltransferase (PNMT) is a critical enzyme in catecholamine synthesis. It transfers the methyl group of S-adenosylmethionine (SAM) to catalyze the synthesis of epinephrine from norepinephrine. Epinephrine has been associated with diverse human processes, including the regulat...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Main Authors: Mahmoodi, Niusha, Harijan, Rajesh K., Schramm, Vern L.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7558223/
https://ncbi.nlm.nih.gov/pubmed/32702980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05446
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