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Pyrophosphate Activation in Hypoxanthine-Guanine Phosphoribosyltransferase with Transition State Analogue

Isotope-edited difference Raman and FTIR studies complemented by ab initio calculations have been applied to the transition state analogue complex of HGPRT●ImmHP●MgPPi to determine the ionic states of the 5’-phosphate moiety of ImmHP and of PPi. These measurements characterize electrostatic interact...

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書誌詳細
主要な著者: Deng, Hua, Callender, Robert, Schramm, Vern L., Grubmeyer, Charles
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851198/
https://ncbi.nlm.nih.gov/pubmed/20170081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100012u
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