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Pyrophosphate Activation in Hypoxanthine-Guanine Phosphoribosyltransferase with Transition State Analogue
Isotope-edited difference Raman and FTIR studies complemented by ab initio calculations have been applied to the transition state analogue complex of HGPRT●ImmHP●MgPPi to determine the ionic states of the 5’-phosphate moiety of ImmHP and of PPi. These measurements characterize electrostatic interact...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851198/ https://ncbi.nlm.nih.gov/pubmed/20170081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100012u |
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