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Immucillin-H, a purine nucleoside phosphorylase transition state analog, causes non-lethal attenuation of growth in Staphylococcus aureus

Purine nucleoside phosphorylase (PNP; EC: 2.4.2.1) is a key enzyme involved in the purine salvage pathway. A recent bioinformatic study by Yadav, P. K. et al. (Bioinformation 2012, 8(14), 664–672) reports PNP as an essential enzyme and potential drug target in community-acquired methicillin-resistan...

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Main Authors: Stratton, Christopher F, Schramm, Vern L
格式: Artigo
語言:Inglês
出版: Biomedical Informatics 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563410/
https://ncbi.nlm.nih.gov/pubmed/23390338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009009
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